A 60-year-old man with hypertension on lisinopril presents with a persistent dry cough for 3 weeks. Vital signs show BP 148/92 mmHg, HR 78/min, RR 16/min. His physician switches to a medication that blocks angiotensin II receptors and effectively lowers blood pressure without increasing bradykinin levels, thus avoiding cough. Chest X-ray shows no infiltrates. Which of the following drugs was most likely prescribed?
- A)Aliskiren
- B)Hydralazine
- C)Spironolactone
- D)LosartanGABARITO
- E)Metoprolol
Explicação
Losartan is an angiotensin II receptor blocker. ARBs reduce vasoconstriction and aldosterone signaling without inhibiting bradykinin breakdown, so they are commonly used when an ACE inhibitor causes cough. Ver explicação completa e trilha adaptativa →