A 20-year-old male presents with progressive weakness and myotonia, most pronounced in the hands and feet. Vital signs show HR 78/min, BP 118/76 mmHg, RR 14/min. Serum creatine kinase is elevated at 2,200 U/L. Muscle biopsy demonstrates prominent ring fibers, centrally located nuclei, and disorganized sarcoplasmic masses. Cardiac examination reveals no arrhythmias. This condition has been associated with a mutation on which of the following chromosomes?
- A)4
- B)19GABARITO
- C)Y
- D)5
- E)X
Explicação
The correct answer is E. Source: Kaplan USMLE Step 1 QBank — Biochemistry Test 2. Ver explicação completa e trilha adaptativa →