A 19-year-old woman with no prior anticoagulant use presents with recurrent epistaxis and menorrhagia since menarche. She reports excessive bleeding for 2 weeks following tooth extraction last month. Vital signs: BP 118/76, HR 88, RR 16, Temp 37°C, SpO2 98%. Laboratory findings reveal platelet count 245,000/μL, bleeding time 12 minutes (prolonged), PTT 38 seconds (mildly prolonged), and normal PT. Which of the following is the most likely diagnosis?
- A)Hemophilia A
- B)Disseminated intravascular coagulation
- C)Bernard-Soulier syndrome
- D)von Willebrand diseaseGABARITO
- E)Immune thrombocytopenia
Explicação
von Willebrand disease is the correct answer because it causes defective platelet adhesion with mucocutaneous bleeding, prolonged bleeding time, and a normal platelet count. PTT can also be mildly prolonged because vWF stabilizes factor VIII. Ver explicação completa e trilha adaptativa →