A 46-year-old man with poorly controlled hypertension (BP 168/102 mmHg) reports progressive enlargement of his hands and feet requiring larger shoe sizes over 3 years, along with intermittent headaches. Examination reveals frontal bossing, prognathism, and coarse facial features. Laboratory studies show elevated insulin-like growth factor 1 (850 ng/mL; normal <200) and fasting glucose 128 mg/dL. Notably, no visual field defects are documented on screening. Which of the following is the best next diagnostic test to confirm the disorder?
- A)Oral glucose tolerance test showing failure of growth hormone suppressionGABARITO
- B)24-hour urine catecholamine measurement
- C)Low dose dexamethasone suppression test
- D)Water deprivation test
- E)ACTH stimulation test
Explicação
Acromegaly is usually caused by a GH secreting pituitary adenoma. Failure of GH suppression by oral glucose confirms the diagnosis. Ver explicação completa e trilha adaptativa →