A 41-year-old woman presents with a 3-month history of fatigue, constipation, weight gain, and cold intolerance. Vital signs show HR 52 bpm, BP 128/82 mmHg, temperature 36.2°C. Physical examination reveals dry skin, delayed relaxation of Achilles reflex, and no thyroid nodules. Laboratory studies demonstrate TSH 8.5 mIU/L (normal 0.4-4.0) and free T4 0.8 ng/dL (normal 0.8-1.8). She denies recent iodine supplement use. Which of the following is the most likely diagnosis?
- A)Hyperthyroidism due to Graves disease
- B)Euthyroid sick syndrome
- C)Secondary hypothyroidism
- D)Primary hypothyroidismGABARITO
- E)Subacute granulomatous thyroiditis
Explicação
Primary hypothyroidism is due to thyroid gland failure, so TSH rises in response to low thyroid hormone production. Ver explicação completa e trilha adaptativa →