A 3-week-old female infant (46, XX) presents with ambiguous genitalia, poor feeding, and lethargy. Vital signs show BP 78/52 mmHg, HR 148/min, RR 32/min, temp 36.8°C. Laboratory studies reveal serum potassium 6.8 mEq/L, sodium 128 mEq/L, and elevated 17-hydroxyprogesterone. Abdominal ultrasound shows normal adrenal glands without hemorrhage. 21-hydroxylase deficiency is confirmed. The adrenal steroid hormones that cannot be synthesized in this patient normally bind to receptors with which of the following characteristics?

1. A)Tyrosine kinase activity
2. B)Helix-loop-helix motif with dyad symmetry
3. C)Seven transmembrane helices
4. D)Guanylate cyclase activity
5. E)Zinc finger motifGABARITO