A 34-year-old African American woman presents with a 3-month history of dry cough, fatigue, and erythema nodosum. Vital signs show BP 118/76, HR 88, RR 18, temp 37.2°C, SpO2 98% on room air. Chest X-ray reveals bilateral hilar lymphadenopathy. Serum calcium is 11.2 mg/dL (elevated), and serum ACE level is 85 U/L (elevated). Pulmonary function tests show normal values. She denies fever, night sweats, or dyspnea. Which of the following is the most likely diagnosis?
- A)Tuberculosis
- B)Silicosis
- C)Berylliosis
- D)Hypersensitivity pneumonitis
- E)SarcoidosisGABARITO
Explicação
Sarcoidosis is a multisystem granulomatous disease characterized by noncaseating granulomas, bilateral hilar adenopathy, erythema nodosum, and elevated ACE levels. Activated macrophages in granulomas can increase 1 alpha hydroxylase activity, causing hypercalc... Ver explicação completa e trilha adaptativa →