A 32-year-old woman presents 2 weeks after pharyngitis with gross hematuria, periorbital edema, and hypertension (BP 148/92 mmHg, HR 88, RR 16, Temp 37.2°C, SpO2 98%). Urinalysis reveals RBC casts and 2+ proteinuria. Serum creatinine is 1.3 mg/dL (baseline 0.8). Complement C3 level is 45 mg/dL (normal 90-180). C4 and ASO titer are normal. She denies arthralgias. Which of the following is the most likely diagnosis?
- A)Systemic lupus erythematosus
- B)Post-streptococcal glomerulonephritisGABARITO
- C)ANCA-associated vasculitis
- D)IgA nephropathy
- E)Hereditary nephritis
Explicação
Post-streptococcal GN typically presents 1-3 weeks after pharyngitis with nephritic syndrome (hematuria, RBC casts, hypertension, edema). Low C3 with normal C4 indicates classical complement pathway activation. Most cases resolve spontaneously in children and ... Ver explicação completa e trilha adaptativa →