A 45-year-old woman presents with progressive proximal muscle weakness, easy bruising, and facial plethora. Her BP is 165/95 mmHg. Laboratory studies show hypokalemia and metabolic alkalosis. An overnight dexamethasone suppression test shows cortisol of 18 µg/dL (normal <5 µg/dL after suppression). Which of the following is the most likely diagnosis?
- A)Thyrotoxicosis
- B)Cushing syndromeGABARITO
- C)Pheochromocytoma
- D)Addison disease
- E)Primary hyperaldosteronism
Explicação
This patient has classic Cushing syndrome: proximal muscle weakness, easy bruising, hypertension, hypokalemia, and metabolic alkalosis. The elevated cortisol after low-dose dexamethasone suppression confirms loss of normal feedback inhibition. Cortisol >5 µg/d... Ver explicação completa e trilha adaptativa →